Quinolines and derivatives
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Filtered Search Results
eMolecules 2-HYDROXYQUINOLINE-6-CARBOXYLIC ACID | 70639-78-0 | MFCD11007961 | 1g
AstaTech | 2-HYDROXYQUINOLINE-6-CARBOXYLIC ACID | 1g | 323612351 | K10089 | 95.000 | 70639-78-0 | MFCD11007961 | 189.170 | C10H7NO3
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Medchemexpress LLC L-Cystathionine dihydrochloride | 61125-50-6 | MFCD00036665 | 99.9% | 295.18 | 25 MG
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L-Cystathionine dihydrochloride is an analytical standard intended for research and analytical applications. This nonprotein thioether is a key amino acid associated with the metabolic state of sulfur-containing amino acids. It protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs) and plays an important role in cardiovascular protection.
- Analytical standard grade for research and analytical applications.
- Nonprotein thioether and key amino acid.
- Protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs).
- Plays an important role in cardiovascular protection.
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
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Medchemexpress LLC Glucocorticoid receptor modulator 1 | 2868357-11-1 | C24H23ClN2O4S | 200 MG
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Glucocorticoid receptor modulator 1 is a highly potent and orally active non-steroidal selective glucocorticoid receptor modulator. It has an IC50 value of 9 nM for NF-κB and 130 nM for AP-1. This product can effectively reduce the expression of inflammatory factors such as IL-6, IL-1β, and TNF-α, and can also relieve dermatitis in mice.
- Highly potent and orally active.
- Non-steroidal selective glucocorticoid receptor modulator.
- Inhibits NF-κB and AP-1 pathways.
- Reduces the expression of inflammatory factors like IL-6, IL-1β, and TNF-α.
- Relieves dermatitis in mice.
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eMolecules 7-HYDROXYQUINOLINE-3-CARBOXYLIC ACID | 659730-27-5 | MFCD18417142 | 1g
AstaTech | 7-HYDROXYQUINOLINE-3-CARBOXYLIC ACID | 1g | 200618830 | 80418 | 95.000 | 659730-27-5 | MFCD18417142 | 189.170 | C10H7NO3
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Medchemexpress LLC 6PPD-Q | 2754428-18-5 | C18H22N2O2 | 25 MG
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6PPD-Q (6PPD-Quinone) is an environmental pollutant detected in human urine and widely present in the environment. It targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 showing the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. It can induce intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation. This compound is applicable for research in environmental toxicology, neurodegenerative diseases, and inflammation-related disorders.
- Targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1
- Acts as a CNR2 receptor agonist
- Induces intestinal inflammation and barrier damage
- Reduces neuronal glycolysis metabolites and TCA cycle intermediates
- Exacerbates α-synuclein (α-syn) aggregation
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Apexbio Technology LLC FLI-06 313967-18-9 25mg
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FLI-06 (CAS 313967-18-9) is a small molecule inhibitor of the Notch signaling pathway exhibiting an EC50 of 2 3 M Notch signaling regulates cell fate decisions and its dysregulation is implicated in oncogenesis and developmental disorders FLI-06 impedes Notch E-eGFP accumulation and reduces NICD-eGFP production in HeLa cells with effects that are fully reversible upon washout indicating low cytotoxicity Additionally FLI-06 significantly decreases A secretion upstream of - and -secretase cleavage events and disrupts Golgi structure by interfering with early secretory pathway membrane trafficking This compound is valuable for studying Notch signaling secretory pathway dynamics and related cellular processes
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Selleck Chemical LLC HOIPIN-8-E1798-5MG
HOIPIN-8 is a potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) and NF- B signaling with an IC50 value of 11 nM It serves as a powerful tool for investigating the physiological and cellular functions of LUBAC
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Accela Chembio Inc 6-bromo-4-hydroxyquinoline | 5g | 145369-94-4 | MFCD00272435 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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6-bromo-4-hydroxyquinoline | 5g | 145369-94-4 | MFCD00272435 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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TARGETMOL CHEMICALS INC YKL-06-062 5MG
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502694129 YKL-06-062 5MG
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Medchemexpress LLC 1,7-Heptanediamine | 646-19-5 | 98.54% | 130.23 | 25 G
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1,7-Heptanediamine (C7) is a deoxyhypusine synthase inhibitor with an IC50 value of 4.5 μM. It is for research use only.
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eMolecules EMOLECULES INC
5000473910 2-METHOXYPYRIDINE-4-CARBA 25MG
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Medchemexpress LLC 8-hydroxyquinoline hemisulfate (8-quinolinol hemisulfate) | 134-31-6 | 100.0% | 194.20 | 500 MG
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8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent that exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.
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Medchemexpress LLC 8-Quinolinol, sulfate (2:1) | 134-31-6 | 99.96% | 194.20 | 1 G
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8-Hydroxyquinoline hemisulfate is a monoprotic bidentate chelating agent. It exhibits antiseptic, disinfectant, and pesticide properties, and functions as a transcription inhibitor.
- Monoprotic bidentate chelating agent
- Antiseptic properties
- Disinfectant properties
- Pesticide properties
- Functions as a transcription inhibitor
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eMolecules EMOLECULES INC
5000473978 ETHYL 4-OXOOXANE-2-CARBO 250MG
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eMolecules EMOLECULES INC
5000473719 2-FLUORO-4-4 4 5 5-TETRAM 10G
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